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To see Prof. Alex Evilevitch Open Researcher and Contributor ID (ORCID), click the link below (it opens another website):https://orcid.org/0000-0002-0245-9574 Below, there is the full list of publication of Prof. Alex Evilevitch. It links to another webpage related to the publisher.Villanueva Valencia J. R., Li D., Casjens S. R., Evilevitch A., "‘SAXS-osmometer’ method provides measurement of
https://www.virus-biophysics.lu.se/publications - 2025-11-17
We use atomic force microscopy (AFM) nano-indentation method to measure DNA mobility in the capsid. The mobility of DNA packaged inside the HSV-1 capsid is measured by recording the force resisting the capsid indentation when the AFM tip is brought into contact with the DNA-filled capsid in solution. Force resisting the AFM tip indentation of the capsid is recorded as the force-distance curve. Cap
https://www.virus-biophysics.lu.se/methods-and-techniques/atomic-force-microscopy - 2025-11-17
We use cryo electron microscopy (cryo-EM) and image reconstruction to examine the virion structure at subnanometer resolution. We also analyze structure and density of viral DNA packaged in a capsid. Figure: Cutaway views from cryo-EM reconstructions of (A) HSV-1 C-capsid and (B) phage lambda procapsid and mature DNA-filled lambda capsid. HSV-1 and lambda phage capsids are shown to scale. Owing t
https://www.virus-biophysics.lu.se/methods-and-techniques/cryo-electron-microscopy - 2025-11-17
The isothermal titration calorimetry (ITC) provides the most direct method to measure the internal energy of the confined viral genome. In order to experimentally dissect the thermodynamic determinants of viral DNA packaging and ejection energetics, we were first to use ITC to directly measure the heat released by DNA ejection from a virus capsid. This approach allows one to address experimentally
https://www.virus-biophysics.lu.se/methods-and-techniques/microcalorimetry - 2025-11-17
Super-Resolution Structured Illumination Microscopy (SR-SIM) provides resolutions down to 120 nm, allowing visualization of individual herpesvirus capsids (HSV-1) attached to the nucleus (HSV-1 C-capsid diameter is 125 nm). Figure: Imaging of reconstituted capsid-nuclei system confirms specific capsid binding to the NPCs at the nuclear membrane. Representative super-resolution SIM image showing G
Despite the structure of packaged viral DNA being central for ejection and consequentially infectivity of the virus, the detailed understanding of the packing structure of DNA inside the viral capsid. SAXS and SANS allow investigation of the structure of DNA filled capsids in solution in a wide range of environmental conditions. SAXS and SANS are powerful techniques that provides detailed structur
For many double stranded (ds) DNA viruses the viral genome is actively packaged into the virus capsid by a powerful molecular motor. This results in an energetically unfavorable state of the packaged genome, creating tens of atmospheres internal pressure inside the virion. Using a new calorimetric assay to determine the activation energy barriers associated with genome loss in response to elevated
https://www.virus-biophysics.lu.se/covers-highlights - 2025-11-17
Följ det Vetenskapsrådsfinansierade forskningsprojektet ”Döden på Vipeholm – en undersökning om vården av ’osnygga obildbara sinnesslöa’ och möjlig medveten dödssvält”. Om projektet Under några av 1940-talets första år dog 200 av de patienter som bodde på Vipeholms sjukhus. Vad berodde det på, att så många dog under de här åren? Kan det ha handlat om eutanasi – vilket har framförts men aldrig lett
https://www.vipeholm.lu.se/vipeholm - 2025-11-17
Artikel av Kristina Engwall i Nordic Journal of Educational History”… äro absolut obildbara”: Barnen på Vipeholm 1935–1963DOI: https://doi.org/10.36368/njedh.v11i1.456Abstract: Hospital in Sweden was the only institution for the ’uneducated, difficult to care for feebleminded’. Although it was designed for adults, a fifth of those admitted were under the age of 15. The article focuses on the child
https://www.vipeholm.lu.se/om-projektet/publicerat - 2025-11-17
Elin Bommenel skriver om sjukhuschefen och överläkaren Hugo Fröderberg Under sitt långa yrkesliv fick Hugo Fröderberg (1897–1986) följa utvecklingen av vad som då kallades ”sinnesslövården”. För eftervärlden kom han att bli känd som sjukhuschef och överläkare på Vipeholms sjukhus – Europas största i sitt slag med plats för nästan 1000 ”svårskötta, obildbara sinnesslöa”. Hugo Fröderberg föddes i Bä
https://www.vipeholm.lu.se/vem-var-hugo-froderberg-och-vad-var-vipeholms-sjukhus - 2025-11-17
Ett tvärvetenskapligt forskningsprojekt om Vipeholm Under krigsåren 1941–1943 dog ett ovanligt stort antal intagna på Vipeholm. Varför vet vi inte med säkerhet ännu. Genom tvärvetenskaplig arkivforskning arbetar fyra forskare med att ta reda på vad som egentligen hände. Hur tar ett välfärdssamhälle hand om sina marginaliserade, mest sårbara invånare? Och hur har synen förändrats på de människor so
https://www.vipeholm.lu.se/om-projektet - 2025-11-17
De deltar i forskningsprojektet ”Döden på Vipeholm” En historiker, en funktionshinderforskare, en idéhistoriker och en medicine doktor specialiserad i psykiatri. Läs mer om deltagarna i det tvärvetenskapliga forskningsprojektet. Elin Bommenel är lektor i Service management och tjänstevetenskap vid Lunds universitet. Där undervisar hon om health management samt om vetenskapsteori, samhällsvetenskap
https://www.vipeholm.lu.se/om-projektet/medverkande - 2025-11-17
You will find the accessible journals on the Library's basement level. In the list they are marked with "in the Library". Shortcuts to the journals A B C D E F H I J K L M N O P Q R S T V,W X Z Use the keyboard shortcut Ctrl + F (for Windows) or ⌘ + F (for Mac) to search the page.Detailed information and conventions in the list of journalsAActa physica polonicaContinued as: Acta Physica Polonica A
https://www.science-library.lu.se/search-and-find/articles-and-journals/journals-physics - 2025-11-17
The Library of Science has several subject guides and resources to help you study or do research. About our subject guidesThe Library of Science subject guides are a good place to start when looking for material such as subject databases, journals, or e-books. The guides can also help you develop your information literacy, writing, and reference management.Shortcuts to the contentGeneral guidesBio
https://www.science-library.lu.se/search-and-find/subject-and-resource-guides - 2025-11-17
The teaching materials you produce are public records and therefore must be deposited in long-term safekeeping or deleted. For advice and help, contact your department director of studies or the Faculty Archivist. Teaching materials which must be deposited Certain materials and documents produced when teaching or supervising students must be archived: Your teaching materials, compendiums, lab inst
https://www.science-library.lu.se/lecturer/records-management-teaching-materials - 2025-11-17
In 200 years, it could be your study that provides the answers. Preserving your research work, is not just about leaving an impression, as the research you are conducting today could prove invaluable for future researchers. Below, you can read about the research documentation that is to be preserved and what is to be disposed of or weeded out. Research documents that must be preserved Discuss the
https://www.science-library.lu.se/researcher-or-doctoral-student/preservation-your-research-work - 2025-11-17
Before you collect data, it is important to plan how to name and organise your files, how to describe your data (which metadata to collect), and which file formats are the appropriate ones to use.Also, consider whether you need any permits, for example from the Swedish Chemicals Agency or the Swedish Radiation Safety Authority. You may also need a permit if you are studying endangered species, tak
There are various costs associated with data management. Be aware of these costs from the outset and allocate the project resources required to cover the outlay. Among the likely costs are: Ethical reviews. Staff to manage the research data (data manager, research engineer). Labour (describing and organising data, data cleansing, de-identification, etc.). Software (purchases or licences). Extra st
About the list of journals Most of our printed journals are located in the closed stack at floor -1, and are not for lending. Come to the library counter and we will get them for you. Scientists and other employees have access to the stack. Scan the articles you need at the photocopier. Shortcuts to the journals A B C D E F G H I J K L M N O P Q R S T V,W Z Ö Use the keyboard shortcut Ctrl + F (fo
https://www.science-library.lu.se/search-and-find/articles-and-journals/journals-chemistry - 2025-11-17
The Library of Science offers courses for doctoral students, workshops, and teaching sessions, and individual guidance regarding information retrieval and scientific communication. We also provide introductions for new employees. Workshops and teaching sessionsThe Library of Science offers workshops and teaching sessions for research teams in these areas:Database searches – Web of Science, BIOSIS,
https://www.science-library.lu.se/researcher-or-doctoral-student/courses-workshops-and-guidance - 2025-11-17
